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A genetic development route analysis on MDS subset carrying initial epigenetic gene mutations

MDS development is a dynamic process during which the accumulation of somatic mutations leads to specific malignant evolution. To elucidate the differential roles of gene mutations in typical MDS, we used targeted sequencing to investigate clonal patterns from 563 patients and focused on cases (199/...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Xu, Feng, Wu, Ling-Yun, Zhao, You-Shan, Guo, Juan, He, Qi, Zhang, Zheng, Chang, Chun-Kang, Wu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972820/
https://www.ncbi.nlm.nih.gov/pubmed/31964915
http://dx.doi.org/10.1038/s41598-019-55540-w