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A genetic development route analysis on MDS subset carrying initial epigenetic gene mutations
MDS development is a dynamic process during which the accumulation of somatic mutations leads to specific malignant evolution. To elucidate the differential roles of gene mutations in typical MDS, we used targeted sequencing to investigate clonal patterns from 563 patients and focused on cases (199/...
Autores principales: | Li, Xiao, Xu, Feng, Wu, Ling-Yun, Zhao, You-Shan, Guo, Juan, He, Qi, Zhang, Zheng, Chang, Chun-Kang, Wu, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972820/ https://www.ncbi.nlm.nih.gov/pubmed/31964915 http://dx.doi.org/10.1038/s41598-019-55540-w |
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