Development of a cognitive function marker based on D-amino acid proportions using new chiral tandem LC-MS/MS systems

The incidence of dementia, a clinical symptom characterized by severe cognitive decline, is increasing worldwide. Predictive biomarkers are therefore required for early identification and management. D-amino acids in the brain contribute to cognitive function and are suggested as useful biomarkers f...

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Detalles Bibliográficos
Autores principales: Kimura, Ren, Tsujimura, Hisashi, Tsuchiya, Masaru, Soga, Satoko, Ota, Noriyasu, Tanaka, Atsushi, Kim, Hunkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972825/
https://www.ncbi.nlm.nih.gov/pubmed/31965028
http://dx.doi.org/10.1038/s41598-020-57878-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972825/
https://www.ncbi.nlm.nih.gov/pubmed/31965028
http://dx.doi.org/10.1038/s41598-020-57878-y

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