Functionalization of remote C(sp(3))-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes

Transition metal catalyzed Sonogashira cross-coupling of terminal alkynes with aryl(vinyl) (pseudo)halides has been successfully extended to alkyl halides for the synthesis of functionalized internal alkynes. The direct alkynylation of remote unfunctionalized sp(3) carbon by terminal alkynes remains...

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Detalles Bibliográficos
Autores principales: Li, Zhaodong, Torres-Ochoa, Rubén O., Wang, Qian, Zhu, Jieping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972843/
https://www.ncbi.nlm.nih.gov/pubmed/31964870
http://dx.doi.org/10.1038/s41467-020-14292-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972843/
https://www.ncbi.nlm.nih.gov/pubmed/31964870
http://dx.doi.org/10.1038/s41467-020-14292-2

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