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Differential Abundance Analysis with Bayes Shrinkage Estimation of Variance (DASEV) for Zero-Inflated Proteomic and Metabolomic Data

Mass spectrometry (MS) is frequently used for proteomic and metabolomic profiling of biological samples. Data obtained by MS are often zero-inflated. Those zero values are called point mass values (PMVs). Zero values can be further grouped into biological PMVs and technical PMVs. The former type is...

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Detalles Bibliográficos
Autores principales: Huang, Zhengyan, Lane, Andrew N., Fan, Teresa W-M., Higashi, Richard M., Weiss, Heidi L., Yin, Xiangrong, Wang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972855/
https://www.ncbi.nlm.nih.gov/pubmed/31964922
http://dx.doi.org/10.1038/s41598-020-57470-4