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Design Strategy to Create Antibody Mimetics Harbouring Immobilised Complementarity Determining Region Peptides for Practical Use

Monoclonal antibodies (mAbs) are attractive therapeutics for treating a wide range of human disorders, and bind to the antigen through their complementarity-determining regions (CDRs). Small stable proteins containing structurally retained CDRs are promising alternatives to mAbs. In this report, we...

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Detalles Bibliográficos
Autores principales: Kadonosono, Tetsuya, Yimchuen, Wanaporn, Ota, Yumi, See, Kyra, Furuta, Tadaomi, Shiozawa, Tadashi, Kitazawa, Maika, Goto, Yu, Patil, Akash, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972867/
https://www.ncbi.nlm.nih.gov/pubmed/31964960
http://dx.doi.org/10.1038/s41598-020-57713-4