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Design Strategy to Create Antibody Mimetics Harbouring Immobilised Complementarity Determining Region Peptides for Practical Use
Monoclonal antibodies (mAbs) are attractive therapeutics for treating a wide range of human disorders, and bind to the antigen through their complementarity-determining regions (CDRs). Small stable proteins containing structurally retained CDRs are promising alternatives to mAbs. In this report, we...
Autores principales: | Kadonosono, Tetsuya, Yimchuen, Wanaporn, Ota, Yumi, See, Kyra, Furuta, Tadaomi, Shiozawa, Tadashi, Kitazawa, Maika, Goto, Yu, Patil, Akash, Kuchimaru, Takahiro, Kizaka-Kondoh, Shinae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972867/ https://www.ncbi.nlm.nih.gov/pubmed/31964960 http://dx.doi.org/10.1038/s41598-020-57713-4 |
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