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FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by amyloid plaques and progressive cerebral atrophy. Here, we report FAM222A as a putative brain atrophy susceptibility gene. Our cross-phenotype association analysis of imaging genetics indicates a potential link between FAM222A and AD-related regional brai...

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Detalles Bibliográficos
Autores principales: Yan, Tingxiang, Liang, Jingjing, Gao, Ju, Wang, Luwen, Fujioka, Hisashi, Zhu, Xiaofeng, Wang, Xinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972869/
https://www.ncbi.nlm.nih.gov/pubmed/31964863
http://dx.doi.org/10.1038/s41467-019-13962-0