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MTAP-deficiency could predict better treatment response in advanced lung adenocarcinoma patients initially treated with pemetrexed-platinum chemotherapy and bevacizumab

To investigate the predictive value of methylthioadenosine phosphorylase (MTAP) on treatment response and survival in advanced lung adenocarcinoma. MTAP expression was detected by immunohistochemistry. Treatment response and survival were compared according to MTAP expression level. The results indi...

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Detalles Bibliográficos
Autores principales: Jing, Wang, Zhu, Hui, Liu, Wenjuan, Zhai, Xiaoyang, Tian, Hairong, Yu, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972892/
https://www.ncbi.nlm.nih.gov/pubmed/31965001
http://dx.doi.org/10.1038/s41598-020-57812-2