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Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis

Chaperonin-containing TCP-1 (CCT or TRiC) is a multi-subunit complex that folds many of the proteins essential for cancer development. CCT is expressed in diverse cancers and could be an ideal therapeutic target if not for the fact that the complex is encoded by eight distinct genes, complicating th...

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Detalles Bibliográficos
Autores principales: Showalter, Anne E., Martini, Ana C., Nierenberg, Daniel, Hosang, Kristen, Fahmi, Naima Ahmed, Gopalan, Priya, Khaled, Amr S., Zhang, Wei, Khaled, Annette R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972895/
https://www.ncbi.nlm.nih.gov/pubmed/31964905
http://dx.doi.org/10.1038/s41598-020-57602-w