Cargando…

Multiscale Process Modelling in Translational Systems Biology of Leishmania major: A Holistic view

Present work aims to utilize systems biology and molecular modelling approach to understand the inhibition kinetics of Leishmania major GLO I and identifying potential hit followed by their validation through in vitro and animal studies. Simulation of GLO I inhibition has shown to affect reaction fl...

Descripción completa

Detalles Bibliográficos
Autores principales: Chauhan, Nutan, Singh, Shailza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972910/
https://www.ncbi.nlm.nih.gov/pubmed/31964958
http://dx.doi.org/10.1038/s41598-020-57640-4