Cargando…

Structure-based development of caged dopamine D(2)/D(3) receptor antagonists

Dopamine is a neurotransmitter of great physiological relevance. Disorders in dopaminergic signal transduction are associated with psychiatric and neurological pathologies such as Parkinson’s disease, schizophrenia and substance abuse. Therefore, a detailed understanding of dopaminergic neurotransmi...

Descripción completa

Detalles Bibliográficos
Autores principales: Gienger, Marie, Hübner, Harald, Löber, Stefan, König, Burkhard, Gmeiner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972920/
https://www.ncbi.nlm.nih.gov/pubmed/31965029
http://dx.doi.org/10.1038/s41598-020-57770-9