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The Role of Peripheral Opioid Receptors in Triggering Heroin-induced Brain Hypoxia

While it is known that opioid receptors (ORs) are densely expressed in both the brain and periphery, it is widely accepted that hypoxic effects of opioids result solely from their direct action in the CNS. To examine the role of peripheral ORs in triggering brain hypoxia, we used oxygen sensors in f...

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Detalles Bibliográficos
Autores principales: Perekopskiy, David, Afzal, Anum, Jackson, Shelley N., Muller, Ludovic, Woods, Amina S., Kiyatkin, Eugene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972941/
https://www.ncbi.nlm.nih.gov/pubmed/31964994
http://dx.doi.org/10.1038/s41598-020-57768-3