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Positive and negative cooperativity of TNF and Interferon-γ in regulating synovial fibroblast function and B cell survival in fibroblast/B cell co-cultures

Synovial fibroblasts (SF) were reported to produce B cell activating factor (BAFF) in response to stimulation with interferon-γ (IFN-γ) or tumor necrosis factor (TNF). However, the influence of these pro-inflammatory cytokines on other receptors/ligands of the TNF superfamily or associated cytokine...

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Detalles Bibliográficos
Autores principales: Lowin, Torsten, Anssar, Tareq M., Bäuml, Marina, Classen, Tim, Schneider, Matthias, Pongratz, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972945/
https://www.ncbi.nlm.nih.gov/pubmed/31964950
http://dx.doi.org/10.1038/s41598-020-57772-7