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A multiple comparison procedure for dose‐finding trials with subpopulations

Identifying subgroups of patients with an enhanced response to a new treatment has become an area of increased interest in the last few years. When there is knowledge about possible subpopulations with an enhanced treatment effect before the start of a trial it might be beneficial to set up a testin...

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Detalles Bibliográficos
Autores principales: Thomas, Marius, Bornkamp, Björn, Posch, Martin, König, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973002/
https://www.ncbi.nlm.nih.gov/pubmed/31544265
http://dx.doi.org/10.1002/bimj.201800111