Proline‐Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii

Proline‐rich antimicrobial peptides (PrAMPs) are promising agents to combat multi‐drug resistant pathogens due to a high antimicrobial activity, yet low cytotoxicity. A library of derivatives of the PrAMP Bac5(1–17) was synthesized and screened to identify which residues are relevant for its activit...

Descripción completa

Detalles Bibliográficos
Autores principales: Mardirossian, Mario, Sola, Riccardo, Beckert, Bertrand, Collis, Dominic W. P., Di Stasi, Adriana, Armas, Federica, Hilpert, Kai, Wilson, Daniel N., Scocchi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973051/
https://www.ncbi.nlm.nih.gov/pubmed/31692278
http://dx.doi.org/10.1002/cmdc.201900465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973051/
https://www.ncbi.nlm.nih.gov/pubmed/31692278
http://dx.doi.org/10.1002/cmdc.201900465

Ejemplares similares