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Peptide‐Based 2‐Aminophenylamide Probes for Targeting Endogenous Class I Histone Deacetylase Complexes

Lysine deacetylases or histone deacetylases (HDACs) remove acetylation markers from numerous cellular proteins, thereby regulating their function and activity. Recently established peptide probes containing the HDAC‐trapping amino acid α‐aminosuberic acid ω‐hydroxamate (AsuHd) have been used to inve...

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Detalles Bibliográficos
Autores principales: Seidel, Julian, Meisinger, Tobias, Sindlinger, Julia, Pieloch, Paulina, Finkemeier, Iris, Schwarzer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973067/
https://www.ncbi.nlm.nih.gov/pubmed/31270913
http://dx.doi.org/10.1002/cbic.201900339