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Protosappanin‐A and oleanolic acid protect injured podocytes from apoptosis through inhibition of AKT‐mTOR signaling

Protosappanin‐A (PrA) and oleanolic acid (OA), which are important effective ingredients isolated from Caesalpinia sappan L., exhibit therapeutic potential in multiple diseases. This study focused on exploring the mechanisms of PrA and OA function in podocyte injury. An in vitro model of podocyte in...

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Detalles Bibliográficos
Autores principales: Zheng, Jiaxin, Zhang, Shoulin, Chen, Huijun, Cai, Xiaojun, Zhang, Chunjian, Li, Shuhua, Zhou, Yabin, Shang, Jing, Liang, Shunyu, Yao, Fengzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973098/
https://www.ncbi.nlm.nih.gov/pubmed/31441181
http://dx.doi.org/10.1002/cbin.11218