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Efficacy, Safety, and Tolerability of ONO‐4474, an Orally Available Pan‐Tropomyosin Receptor Kinase Inhibitor, in Japanese Patients With Moderate to Severe Osteoarthritis of the Knee: A Randomized, Placebo‐Controlled, Double‐Blind, Parallel‐Group Comparative Study

We examined the efficacy, safety, and tolerability of ONO‐4474 in Japanese patients with osteoarthritis (OA) of the knee. In this multicenter, placebo‐controlled, randomized, double‐blind, parallel‐group comparative study, patients with moderate to severe OA who were refractory to nonsteroidal anti‐...

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Detalles Bibliográficos
Autores principales: Ishiguro, Naoki, Oyama, Shusuke, Higashi, Ryunosuke, Yanagida, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973102/
https://www.ncbi.nlm.nih.gov/pubmed/31281988
http://dx.doi.org/10.1002/jcph.1470