Voltage‐dependent activation of Rac1 by Na(v)1.5 channels promotes cell migration

Ion channels can regulate the plasma membrane potential (V(m)) and cell migration as a result of altered ion flux. However, the mechanism by which V(m) regulates motility remains unclear. Here, we show that the Na(v)1.5 sodium channel carries persistent inward Na(+) current which depolarizes the res...

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Detalles Bibliográficos
Autores principales: Yang, Ming, James, Andrew D., Suman, Rakesh, Kasprowicz, Richard, Nelson, Michaela, O'Toole, Peter J., Brackenbury, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973152/
https://www.ncbi.nlm.nih.gov/pubmed/31612502
http://dx.doi.org/10.1002/jcp.29290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973152/
https://www.ncbi.nlm.nih.gov/pubmed/31612502
http://dx.doi.org/10.1002/jcp.29290

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