One‐Step Synthesis of 2,5‐Diaminoimidazoles and Total Synthesis of Methylglyoxal‐Derived Imidazolium Crosslink (MODIC)

Here we describe a general method for the synthesis of 2,5‐diaminoimidazoles, which involves a thermal reaction between α‐aminoketones and substituted guanylhydrazines without the need for additives. As one of the few known ways to access the 2,5‐diaminoimidazole motif, our method greatly expands th...

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Detalles Bibliográficos
Autores principales: Sabbasani, Venkata R., Wang, Kung‐Pern, Streeter, Matthew D., Spiegel, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973230/
https://www.ncbi.nlm.nih.gov/pubmed/31713976
http://dx.doi.org/10.1002/anie.201911156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973230/
https://www.ncbi.nlm.nih.gov/pubmed/31713976
http://dx.doi.org/10.1002/anie.201911156

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