Electrochemical Vicinal Difluorination of Alkenes: Scalable and Amenable to Electron‐Rich Substrates

Fluorinated alkyl groups are important motifs in bioactive compounds, positively influencing pharmacokinetics, potency and conformation. The oxidative difluorination of alkenes represents an important strategy for their preparation, yet current methods are limited in their alkene‐types and tolerance...

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Detalles Bibliográficos
Autores principales: Doobary, Sayad, Sedikides, Alexi T., Caldora, Henry P., Poole, Darren L., Lennox, Alastair J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973232/
https://www.ncbi.nlm.nih.gov/pubmed/31697872
http://dx.doi.org/10.1002/anie.201912119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973232/
https://www.ncbi.nlm.nih.gov/pubmed/31697872
http://dx.doi.org/10.1002/anie.201912119

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