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Gata3 targets Runx1 in the embryonic haematopoietic stem cell niche

Runx1 is an important haematopoietic transcription factor as stressed by its involvement in a number of haematological malignancies. Furthermore, it is a key regulator of the emergence of the first haematopoietic stem cells (HSCs) during development. The transcription factor Gata3 has also been link...

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Detalles Bibliográficos
Autores principales: Fitch, Simon R., Kapeni, Chrysa, Tsitsopoulou, Aikaterini, Wilson, Nicola K., Göttgens, Berthold, de Bruijn, Marella F., Ottersbach, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973286/
https://www.ncbi.nlm.nih.gov/pubmed/31634421
http://dx.doi.org/10.1002/iub.2184