Rapid two-dimensional Protein-A size exclusion chromatography of monoclonal antibodies for titer and aggregation measurements from harvested cell culture fluid samples

The success of monoclonal antibody (mAb) therapeutics have increased pharmaceutical investment in mAb production, which has led to a greater demand of technologies to efficiently characterize these biotherapeutics. The large size and heterogeneity of mAbs require the measurement of multiple critical...

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Detalles Bibliográficos
Autores principales: Dunn, Zachary D., Desai, Jayesh, Leme, Gabriel M., Stoll, Dwight R., Richardson, Douglas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973321/
https://www.ncbi.nlm.nih.gov/pubmed/31876441
http://dx.doi.org/10.1080/19420862.2019.1702263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973321/
https://www.ncbi.nlm.nih.gov/pubmed/31876441
http://dx.doi.org/10.1080/19420862.2019.1702263

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