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Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer

BACKGROUND: Colorectal cancer remains a deadly cancer due to metastatic disease. To understand the molecular mechanisms of metastasis in colon cancer, we investigated whether the copper chaperone antioxidant-1 (Atox1) protein plays a role in this process. Recent findings indicate that Atox1 protein...

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Detalles Bibliográficos
Autores principales: Jana, Arundhati, Das, Archita, Krett, Nancy L., Guzman, Grace, Thomas, Alexandra, Mancinelli, Georgina, Bauer, Jessica, Ushio-Fukai, Masuko, Fukai, Tohru, Jung, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974162/
https://www.ncbi.nlm.nih.gov/pubmed/31961892
http://dx.doi.org/10.1371/journal.pone.0227916