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Cryo electron tomography with volta phase plate reveals novel structural foundations of the 96-nm axonemal repeat in the pathogen Trypanosoma brucei

The 96-nm axonemal repeat includes dynein motors and accessory structures as the foundation for motility of eukaryotic flagella and cilia. However, high-resolution 3D axoneme structures are unavailable for organisms among the Excavates, which include pathogens of medical and economic importance. Her...

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Detalles Bibliográficos
Autores principales: Imhof, Simon, Zhang, Jiayan, Wang, Hui, Bui, Khanh Huy, Nguyen, Hoangkim, Atanasov, Ivo, Hui, Wong H, Yang, Shun Kai, Zhou, Z Hong, Hill, Kent L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974359/
https://www.ncbi.nlm.nih.gov/pubmed/31710293
http://dx.doi.org/10.7554/eLife.52058