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Identifying cross-disease components of genetic risk across hospital data in the UK Biobank

Genetic risk factors frequently affect multiple common human diseases, providing insight into shared pathophysiological pathways and opportunities for therapeutic development. However, systematic identification of genetic profiles of disease risk is limited by the availability of both comprehensive...

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Detalles Bibliográficos
Autores principales: Cortes, Adrian, Albers, Patrick K., Dendrou, Calliope A., Fugger, Lars, McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974401/
https://www.ncbi.nlm.nih.gov/pubmed/31873298
http://dx.doi.org/10.1038/s41588-019-0550-4