Astragalus polysaccharide attenuates metabolic memory-triggered ER stress and apoptosis via regulation of miR-204/SIRT1 axis in retinal pigment epithelial cells

Background: ‘Metabolic memory’ of early hyperglycaemic environment has been frequently suggested in the progression of diabetic retinopathy (DR). Retinal pigment epithelial (RPE) cells are crucial targets for DR initiation following hyperglycaemia. Astragalus polysaccharides (APS) has been long used...

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Detalles Bibliográficos
Autores principales: Peng, Qing-Hua, Tong, Ping, Gu, Li-Min, Li, Wen-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Diabetes & Metabolic Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974424/
https://www.ncbi.nlm.nih.gov/pubmed/31894851
http://dx.doi.org/10.1042/BSR20192121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974424/
https://www.ncbi.nlm.nih.gov/pubmed/31894851
http://dx.doi.org/10.1042/BSR20192121

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