Cytokine Production and NET Formation by Monosodium Urate-Activated Human Neutrophils Involves Early and Late Events, and Requires Upstream TAK1 and Syk

Gout is a prevalent and incapacitating disease triggered by the deposition of monosodium urate (MSU) crystals in joints, which are also massively infiltrated by neutrophils. The interaction of the latter with MSU crystals triggers several responses, including the generation of inflammatory mediators...

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Detalles Bibliográficos
Autores principales: Tatsiy, Olga, Mayer, Thomas Z., de Carvalho Oliveira, Vanessa, Sylvain-Prévost, Stéphanie, Isabel, Marilyn, Dubois, Claire M., McDonald, Patrick P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974451/
https://www.ncbi.nlm.nih.gov/pubmed/32010124
http://dx.doi.org/10.3389/fimmu.2019.02996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974451/
https://www.ncbi.nlm.nih.gov/pubmed/32010124
http://dx.doi.org/10.3389/fimmu.2019.02996

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