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DGK α and ζ Activities Control T(H)1 and T(H)17 Cell Differentiation

CD4(+) T helper (T(H)) cells are critical for protective adaptive immunity against pathogens, and they also contribute to the pathogenesis of autoimmune diseases. How T(H) differentiation is regulated by the TCR's downstream signaling is still poorly understood. We describe here that diacylglyc...

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Detalles Bibliográficos
Autores principales: Yang, Jialong, Wang, Hong-Xia, Xie, Jinhai, Li, Lei, Wang, Jinli, Wan, Edwin C. K., Zhong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974463/
https://www.ncbi.nlm.nih.gov/pubmed/32010133
http://dx.doi.org/10.3389/fimmu.2019.03048