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egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation
Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and hindering the immune response against bacterial in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974467/ https://www.ncbi.nlm.nih.gov/pubmed/32010128 http://dx.doi.org/10.3389/fimmu.2019.03008 |