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egc Superantigens Impair Monocytes/Macrophages Inducing Cell Death and Inefficient Activation

Bacterial superantigens (SAgs) are enterotoxins that bind to MHC-II and TCR molecules, activating as much as 20% of the T cell population and promoting a cytokine storm which enhances susceptibility to endotoxic shock, causing immunosuppression, and hindering the immune response against bacterial in...

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Detalles Bibliográficos
Autores principales: Noli Truant, Sofia, De Marzi, Mauricio C., Sarratea, María B., Antonoglou, María B., Meo, Ana P., Iannantuono López, Laura V., Fernández Lynch, María J., Todone, Marcos, Malchiodi, Emilio L., Fernández, Marisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974467/
https://www.ncbi.nlm.nih.gov/pubmed/32010128
http://dx.doi.org/10.3389/fimmu.2019.03008