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Using Precisely Defined in vivo Microbiotas to Understand Microbial Regulation of IgE
Early life exposure to microbes plays an important role in immune system development. Germ-free mice, or mice colonized with a low-diversity microbiota, exhibit high serum IgE levels. An increase in microbial richness, providing it occurs in a critical developmental window early in life, leads to in...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974480/ https://www.ncbi.nlm.nih.gov/pubmed/32010146 http://dx.doi.org/10.3389/fimmu.2019.03107 |