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Head-to-head comparison of tau positron emission tomography tracers [(18)F]flortaucipir and [(18)F]RO948

PURPOSE: [(18)F]flortaucipir binds to paired helical filament tau and accurately identifies tau in Alzheimer’s disease (AD). However, “off-target” binding interferes with the quantification of [(18)F]flortaucipir in several brain regions. Recently, other tau PET tracers have been developed. Here, we...

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Detalles Bibliográficos
Autores principales: Smith, Ruben, Schöll, Michael, Leuzy, Antoine, Jögi, Jonas, Ohlsson, Tomas, Strandberg, Olof, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974501/
https://www.ncbi.nlm.nih.gov/pubmed/31612245
http://dx.doi.org/10.1007/s00259-019-04496-0