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IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag

Interferon-induced transmembrane (IFITM) proteins are encoded by many vertebrate species and exhibit antiviral activities against a wide range of viruses. IFITM3, when present in virus-producing cells, reduces the fusion potential of HIV-1 virions, but the mechanism is poorly understood. To define t...

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Detalles Bibliográficos
Autores principales: Ahi, Yadvinder S., Yimer, Diborah, Shi, Guoli, Majdoul, Saliha, Rahman, Kazi, Rein, Alan, Compton, Alex A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974572/
https://www.ncbi.nlm.nih.gov/pubmed/31964738
http://dx.doi.org/10.1128/mBio.03088-19