In Situ Activation and Heterologous Production of a Cryptic Lantibiotic from an African Plant Ant-Derived Saccharopolyspora Species

Most clinical antibiotics are derived from actinomycete natural products discovered at least 60 years ago. However, the repeated rediscovery of known compounds led the pharmaceutical industry to largely discard microbial natural products (NPs) as a source of new chemical diversity. Recent advances i...

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Detalles Bibliográficos
Autores principales: Vikeli, Eleni, Widdick, David A., Batey, Sibyl F. D., Heine, Daniel, Holmes, Neil A., Bibb, Mervyn J., Martins, Dino J., Pierce, Naomi E., Hutchings, Matthew I., Wilkinson, Barrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974636/
https://www.ncbi.nlm.nih.gov/pubmed/31732571
http://dx.doi.org/10.1128/AEM.01876-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974636/
https://www.ncbi.nlm.nih.gov/pubmed/31732571
http://dx.doi.org/10.1128/AEM.01876-19

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