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Amelioration of age‐related brain function decline by Bruton's tyrosine kinase inhibition

One of the hallmarks of aging is the progressive accumulation of senescent cells in organisms, which has been proposed to be a contributing factor to age‐dependent organ dysfunction. We recently reported that Bruton's tyrosine kinase (BTK) is an upstream component of the p53 responses to DNA da...

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Detalles Bibliográficos
Autores principales: Ekpenyong‐Akiba, Akang E., Poblocka, Marta, Althubiti, Mohammad, Rada, Miran, Jurk, Diana, Germano, Sandra, Kocsis‐Fodor, Gabriella, Shi, Yu, Canales, Juan J., Macip, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974713/
https://www.ncbi.nlm.nih.gov/pubmed/31736210
http://dx.doi.org/10.1111/acel.13079