mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging

Cerebrovascular dysfunction and cognitive decline are highly prevalent in aging, but the mechanisms underlying these impairments are unclear. Cerebral blood flow decreases with aging and is one of the earliest events in the pathogenesis of Alzheimer's disease (AD). We have previously shown that...

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Detalles Bibliográficos
Autores principales: Van Skike, Candice E., Lin, Ai‐Ling, Roberts Burbank, Raquel, Halloran, Jonathan J., Hernandez, Stephen F., Cuvillier, James, Soto, Vanessa Y., Hussong, Stacy A., Jahrling, Jordan B., Javors, Martin A., Hart, Matthew J., Fischer, Kathleen E., Austad, Steven N., Galvan, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974719/
https://www.ncbi.nlm.nih.gov/pubmed/31693798
http://dx.doi.org/10.1111/acel.13057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974719/
https://www.ncbi.nlm.nih.gov/pubmed/31693798
http://dx.doi.org/10.1111/acel.13057

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