Longevity in response to lowered insulin signaling requires glycine N‐methyltransferase‐dependent spermidine production

Reduced insulin/IGF signaling (IIS) extends lifespan in multiple organisms. Different processes in different tissues mediate this lifespan extension, with a set of interplays that remain unclear. We here show that, in Drosophila, reduced IIS activity modulates methionine metabolism, through tissue‐s...

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Detalles Bibliográficos
Autores principales: Tain, Luke S., Jain, Chirag, Nespital, Tobias, Froehlich, Jenny, Hinze, Yvonne, Grönke, Sebastian, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974722/
https://www.ncbi.nlm.nih.gov/pubmed/31721422
http://dx.doi.org/10.1111/acel.13043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974722/
https://www.ncbi.nlm.nih.gov/pubmed/31721422
http://dx.doi.org/10.1111/acel.13043

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