Rap1‐mediated nucleosome displacement can regulate gene expression in senescent cells without impacting the pace of senescence

Cell senescence is accompanied, and in part mediated, by changes in chromatin, including histone losses, but underlying mechanisms are not well understood. We reported previously that during yeast cell senescence driven by telomere shortening, the telomeric protein Rap1 plays a major role in reprogr...

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Detalles Bibliográficos
Autores principales: Song, Shufei, Perez, Javier V., Svitko, William, Ricketts, M. Daniel, Dean, Elliot, Schultz, David, Marmorstein, Ronen, Johnson, F. Brad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974733/
https://www.ncbi.nlm.nih.gov/pubmed/31742863
http://dx.doi.org/10.1111/acel.13061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974733/
https://www.ncbi.nlm.nih.gov/pubmed/31742863
http://dx.doi.org/10.1111/acel.13061

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