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Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives

The ability to engineer pharmaceuticals that target the signal-dependent interactions of signaling proteins should revolutionize drug development. One approach to the rational design of protein interaction inhibitors uses decoy peptides, i.e. segments of protein primary sequence, which are derived f...

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Detalles Bibliográficos
Autores principales: Toshchakov, Vladimir Y, Javmen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974878/
https://www.ncbi.nlm.nih.gov/pubmed/31955621
http://dx.doi.org/10.1177/1753425919844310