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Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives
The ability to engineer pharmaceuticals that target the signal-dependent interactions of signaling proteins should revolutionize drug development. One approach to the rational design of protein interaction inhibitors uses decoy peptides, i.e. segments of protein primary sequence, which are derived f...
Autores principales: | Toshchakov, Vladimir Y, Javmen, Artur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974878/ https://www.ncbi.nlm.nih.gov/pubmed/31955621 http://dx.doi.org/10.1177/1753425919844310 |
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