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Select targeting of intracellular Toll-interleukin-1 receptor resistance domains for protection against influenza-induced disease

TLRs are a family of PRRs that respond to PAMPs or host-derived Danger-Associated Molecular Patterns (DAMPs) to initiate host inflammation and immune responses. TLR dimerization and recruitment of adapter molecules is critical for intracellular signaling and is mediated through intracellular Toll-In...

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Detalles Bibliográficos
Autores principales: Shirey, Kari Ann, Lai, Wendy, Brown, Lindsey J, Blanco, Jorge C G, Beadenkopf, Robert, Wang, Yajing, Vogel, Stefanie N, Snyder, Greg A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974880/
https://www.ncbi.nlm.nih.gov/pubmed/31955622
http://dx.doi.org/10.1177/1753425919846281