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Nanoscopic Insights of Amphiphilic Peptide against the Oligomer Assembly Process to Treat Huntington's Disease

Finding an effective therapeutic regimen is an urgent demand for various neurodegenerative disorders including Huntington's disease (HD). For the difficulties in observing the dynamic aggregation and oligomerization process of mutant Huntingtin (mHtt) in vivo, the evaluation of potential drugs...

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Detalles Bibliográficos
Autores principales: He, Ruei‐Yu, Lai, Xiang‐Me, Sun, Chia‐Sui, Kung, Te‐Shien, Hong, Jhu‐Ying, Jheng, Yu‐Song, Liao, Wei‐Neng, Chen, Jen‐Kun, Liao, Yung‐Feng, Tu, Pang‐Hsien, Huang, Joseph Jen‐Tse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974936/
https://www.ncbi.nlm.nih.gov/pubmed/31993280
http://dx.doi.org/10.1002/advs.201901165