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Nanoscopic Insights of Amphiphilic Peptide against the Oligomer Assembly Process to Treat Huntington's Disease
Finding an effective therapeutic regimen is an urgent demand for various neurodegenerative disorders including Huntington's disease (HD). For the difficulties in observing the dynamic aggregation and oligomerization process of mutant Huntingtin (mHtt) in vivo, the evaluation of potential drugs...
Autores principales: | He, Ruei‐Yu, Lai, Xiang‐Me, Sun, Chia‐Sui, Kung, Te‐Shien, Hong, Jhu‐Ying, Jheng, Yu‐Song, Liao, Wei‐Neng, Chen, Jen‐Kun, Liao, Yung‐Feng, Tu, Pang‐Hsien, Huang, Joseph Jen‐Tse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974936/ https://www.ncbi.nlm.nih.gov/pubmed/31993280 http://dx.doi.org/10.1002/advs.201901165 |
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