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DNA‐Mediated Assembly of Multispecific Antibodies for T Cell Engaging and Tumor Killing

Targeting T‐cells against cancer cells is a direct means of treating cancer, and has already shown great responses in clinical treatment of B‐cell malignancies. A simple way to redirect T‐cells to cancer cells is by using multispecific antibody (MsAb) that contains different arms for specifically “g...

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Detalles Bibliográficos
Autores principales: Pan, Liqiang, Cao, Chan, Run, Changqing, Zhou, Liujuan, Chou, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974939/
https://www.ncbi.nlm.nih.gov/pubmed/31993277
http://dx.doi.org/10.1002/advs.201900973