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5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease

BACKGROUND: The 5-hydroxymethylcytosine (5hmC) DNA modification is an epigenetic marker involved in a range of biological processes. Its function has been studied extensively in tumors, neurodegenerative diseases, and atherosclerosis. Studies have reported that 5hmC modification is closely related t...

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Detalles Bibliográficos
Autores principales: Dong, Chaoran, Chen, Jiemei, Zheng, Jilin, Liang, Yiming, Yu, Tao, Liu, Yupeng, Gao, Feng, Long, Jie, Chen, Hangyu, Zhu, Qianhui, He, Zilong, Hu, Songnian, He, Chuan, Lin, Jian, Tang, Yida, Zhu, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974971/
https://www.ncbi.nlm.nih.gov/pubmed/31964422
http://dx.doi.org/10.1186/s13148-020-0810-2