Late clinical failure associated with cytochrome b codon 268 mutation during treatment of falciparum malaria with atovaquone–proguanil in traveller returning from Congo

BACKGROUND: The drug combination atovaquone–proguanil, is recommended for treatment of uncomplicated falciparum malaria in France. Despite high efficacy, atovaquone–proguanil treatment failures have been reported. Resistance to cycloguanil, the active metabolite of proguanil, is conferred by multipl...

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Detalles Bibliográficos
Autores principales: Massamba, Laurencie, Madamet, Marylin, Benoit, Nicolas, Chevalier, Alicia, Fonta, Isabelle, Mondain, Véronique, Jeandel, Pierre-Yves, Amalvict, Rémy, Delaunay, Pascal, Mosnier, Joel, Marty, Pierre, Pomares, Christelle, Pradines, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975030/
https://www.ncbi.nlm.nih.gov/pubmed/31964401
http://dx.doi.org/10.1186/s12936-020-3126-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975030/
https://www.ncbi.nlm.nih.gov/pubmed/31964401
http://dx.doi.org/10.1186/s12936-020-3126-y

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