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Establishment of EMab-134, a Sensitive and Specific Anti-Epidermal Growth Factor Receptor Monoclonal Antibody for Detecting Squamous Cell Carcinoma Cells of the Oral Cavity

Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, activates downstream signaling cascades in many tumors. In this study, we established novel anti-EGFR monoclonal antibodies (mAbs) and characterized their efficacy in flow cytometry, Western blot, and immunohistochemical analyses....

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Detalles Bibliográficos
Autores principales: Itai, Shunsuke, Yamada, Shinji, Kaneko, Mika K., Chang, Yao-Wen, Harada, Hiroyuki, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975130/
https://www.ncbi.nlm.nih.gov/pubmed/29090976
http://dx.doi.org/10.1089/mab.2017.0042