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Establishment of EMab-134, a Sensitive and Specific Anti-Epidermal Growth Factor Receptor Monoclonal Antibody for Detecting Squamous Cell Carcinoma Cells of the Oral Cavity
Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, activates downstream signaling cascades in many tumors. In this study, we established novel anti-EGFR monoclonal antibodies (mAbs) and characterized their efficacy in flow cytometry, Western blot, and immunohistochemical analyses....
Autores principales: | Itai, Shunsuke, Yamada, Shinji, Kaneko, Mika K., Chang, Yao-Wen, Harada, Hiroyuki, Kato, Yukinari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975130/ https://www.ncbi.nlm.nih.gov/pubmed/29090976 http://dx.doi.org/10.1089/mab.2017.0042 |
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