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Long-term adenosine A1 receptor activation-induced sortilin expression promotes α-synuclein upregulation in dopaminergic neurons

Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development of neurodegenerative diseases. However, the pathogenesis underlying long-term adenosine A1 receptor activation-induced neurodegeneration remains unclear. In this study, rats were i...

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Detalles Bibliográficos
Autores principales: Lv, Yun-Cheng, Gao, An-Bo, Yang, Jing, Zhong, Li-Yuan, Jia, Bo, Ouyang, Shu-Hui, Gui, Le, Peng, Tian-Hong, Sun, Sha, Cayabyab, Francisco S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975149/
https://www.ncbi.nlm.nih.gov/pubmed/31638096
http://dx.doi.org/10.4103/1673-5374.266916